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Synthetic biology
+
Computational Biology
for Drug Discovery

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About Guido

Hi, my name is Guido, and my mission is to create new therapeutics for people's health with Synthetic Biology. I want to impact billions of people positively, and I constantly work to improve myself and anyone around me.
I know the journey is challenging, but anyone would have done that if it wasn't this way.
"The quality of your mind determines the quality of your life." I think that the most important asset is to care about what you're feeling constantly.

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My Interests

Treating Biology like Technology

I love the idea of using biology like technology. I have always noticed the importance of having computational methods that can describe and forecast how our biology is. I studied computational approaches with Quantum Computers to understand Protein Folding to solve the leviathan paradox.

Drug Discovery with Artificial Intelligence

My mission in life is to create new therapeutics to help patients'health. I have already worked in the field of Protein Inactivation for Nociceptors and now I'm going deeper in how to use Computational Approaches for De Novo Design and QSAR modeling

Ageing as a Disease

Let's imagine how we can work towards the creation of new therapeutics to treat the mother of all diseases: ageing. I have worked toward studying Computational Biology approaches to study and define different ageing processes.


Skills and tools

I work in the field of synthetic biology, with the focus on engineering mammalian cells to create new therapeutics for chronic diseases.

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My Core Values

Focus

Our world is incredibly complex and specialized. Sometimes the fastest way to find solutions is by thinking about them independently

Curiosity

I want to go deeper into what I know already. I want to explore new horizons to understand new possibilities

High Standards

Having high standards is an example of caring so much about your mission that you need to invest time and energy to accomplish it

Helpful

I'm in the world to serve humanity and to make our universe a better place where to live

Optimism

Optimism is the trait that makes me work so hard to achieve what I want in the world

Impacting Billions

I want to focus on bioengineering solutions that can impact the world. It's all about purpose minimalism


Evolutionary Cancer Dynamics

Exercises in Game Theory, selection, diffusion, cooperation and much more to model cancer dynamics.

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Statistical Analysis for High-throughput Screening

Several projects on ATACseq, RNAseq and statistical analysis.

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Computational Simulation of Biomolecular Systems

6 Projects to study and simulate biomolecules

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Understanding human brain development and diseases: Lamin morphodynamics in brain organoids

Organoids are three-dimensional tissues grown from stem cells that can self-organize and differentiate to form different cell types and tissue architectures similar to organs. Lamins are structural proteins of the cell nucleus that regulate and support protein complexes involved in gene expression, DNA replication, transcription and repair, nuclear positioning, and aging. The function of lamins in brain organoid development is unclear.

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Bioimage analysis for stem cell research

A stem cell is a type of cell that has the unique ability to differentiate into various specialized cell types in the body. Stem cells are undifferentiated and unspecialized, which means they do not have a specific function or structure in the body like other

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Towards AI-driven longevity research: An overview

The process of aging is known to be dependent upon the interaction of different factors,such as the genome content of an individual, lifestyle factors, environmental interaction, and health facilities available to the individual (Newman and Murabito, 2013; Partridge et al., 2018; Singh et al., 2019). Increased lifespan and age represent the exceptional survival, maintenance of good health as compared to peers, delayed onsets of age-dependent diseases, and extreme phenotype of individuals (Kaeberlein, 2018; Pignolo, 2019). Previous works have emphasized how modern Artificial Intelligence (AI) is already playing an important role in speeding up decision-making in medical sciences by means of advanced machine learning (ML) algorithms. For example, it is revolutionizing the drug discovery process, saving money and time (Kelemen et al., 2008), as it is already being used to create the structure of new drugs depending on the specific structure of the target diseasecausing compound [see (Santus et al., 2021) for an overview]. In life sciences, the generation of high-throughput data such as proteomics, genomics, chemoproteomics and phenomics

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Synthetic biology for Entrepreneurs: Innovations in the Healthcare Sector

Imagine if you can have a tree that can mine gold or be resistant to any kind of virus forever.

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Stem Cells, What they are, How to use them and their future implications

Imagine if you could cure many diseases such as AIDS, Diabetes, Stroke and Alzheimer with just one element, would you be astonished by that?

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What is Human Enhancement, and why is it good for our society?

It was one day like others when the 20th October 1890 Walter Yeo was born. He was a young guy like others who used to spend his days with his older sisters Adelaide and Elsie.

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Awards


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