Guido Putignano - Engineer & Computational Biologist

About Guido

I'm Guido Putignano, a scientist and entrepreneur at the intersection of cell therapy, control theory and artificial intelligence. My mission is to revolutionize healthcare by developing novel therapeutic approaches that combine synthetic biology with advanced engineering principles.

I focus on addressing major challenges in chronic diseases including cancer, diabetes, and neurodegenerative conditions. Through my work in optimal control systems and cell biology, I aim to create scalable solutions that can impact millions of lives.

What drives me is the belief that breakthrough innovations come from bridging disciplines – from biomedical engineering to AI-powered predictions. I'm committed to both scientific excellence and building the communities and platforms that accelerate progress in biotech.

"The quality of your mind determines the quality of your life." I'm dedicated to continuous learning and growth, both in scientific understanding and in building meaningful relationships that drive progress.

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My Interests

Analyzing Biology

Let's reimagine aging as a treatable disease. My computational approaches decode biological processes at the molecular level, identifying intervention points to address the mother of all diseases. This paves the way for targeted age-related therapeutics.

Automate Experiment

I enhance research through intelligent automation. My systems design optimized experiments that minimize costs while maximizing insights. By applying AI to laboratory workflows, we can accelerate discovery timelines and improve reproducibility in biological research.

Control Biology

My mission is developing next-generation cell therapies. By applying control theory to biological systems, I create technologies for precisely engineered treatments, aiming for cures rather than chronic management.

My Core Values

Focus

Diving deep into specific problems to uncover solutions others miss. Complex challenges require concentrated attention and independent thinking.

Self-Sustaining Systems

Creating systems that generate value autonomously. True impact comes from solutions that outlast their creator.

Empathy

Pursuing excellence while remembering people come first. Impact matters, but so does how we treat each other along the way.

Purpose-Driven

Serving humanity by solving real problems. Motivated by creating positive change that improves lives.

Resilience

Adapting to setbacks rather than being defeated. This powers the pursuit of ambitious goals despite obstacles.

Impacting Billions

Focusing on bioengineering solutions with global reach. Purpose minimalism at its core.

Portfolio

Academic Journey: From Biomedical Engineering to Computational Biology

Description of the courses I have taken and my comments on them

AI ethics for children: digital natives on how to protect future generations

Children and young people are growing up in an increasingly digital age, where technology pervades every aspect of their lives. From robotic toys and social media to the classroom and home, artificial intelligence (AI) is a ubiquitous part of daily life.

Towards AI-driven longevity research: An overview

An overview of how modern Artificial Intelligence is revolutionizing longevity research and drug discovery, analyzing high-throughput data from proteomics, genomics, and phenomics.

Synthetic biology for Entrepreneurs: Innovations in the Healthcare Sector

Imagine if you can have a tree that can mine gold or be resistant to any kind of virus forever.

Stem Cells, What they are, How to use them and their future implications

Imagine if you could cure many diseases such as AIDS, Diabetes, Stroke and Alzheimer with just one element, would you be astonished by that?

What is Human Enhancement, and why is it good for our society?

It was one day like others when the 20th October 1890 Walter Yeo was born. He was a young guy like others who used to spend his days with his older sisters Adelaide and Elsie.

Optimising Endothelialisation in VADs through Mechanoengineering and Predictive Control

This repository contains the code and documentation for optimizing endothelialisation in Ventricular Assist Devices (VADs) using Model Predictive Control (MPC).

Evolutionary Cancer Dynamics

Exercises in Game Theory, selection, diffusion, cooperation and much more to model cancer dynamics.

Statistical Analysis for High-throughput Screening

Several projects on ATACseq, RNAseq and statistical analysis.

Computational Simulation of Biomolecular Systems

6 Projects to study and simulate biomolecules

Understanding human brain development and diseases: Lamin morphodynamics in brain organoids

Organoids are three-dimensional tissues grown from stem cells that can self-organize and differentiate to form different cell types and tissue architectures similar to organs. Lamins are structural proteins of the cell nucleus that regulate and support protein complexes involved in gene expression, DNA replication, transcription and repair, nuclear positioning, and aging. The function of lamins in brain organoid development is unclear.

Bioimage analysis for stem cell research

A stem cell is a type of cell that has the unique ability to differentiate into various specialized cell types in the body. Stem cells are undifferentiated and unspecialized, which means they do not have a specific function or structure in the body like other cells.